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Title: 4 cases from suspected chronic granulomatous disease in the respiratory unit in Vietnam national children's hospital
Authors: Dang Mai Lien
Le Thi Hong Hanh
Trinh Thi Dung
Keywords: chronic granulomatous disease; persistent pneumonia
Issue Date: 2020
Publisher: Journal of Medical Research
Series/Report no.: 136 (12);
Abstract: Chronic granulomatous disease (CGD) is an inherited primary immunodeficiency disease which is one kind of the phagocytic dysfunction. It is accounted for 1 : 200000 live births in the United States. The mechanism of CGD is mutation in any structural molecules of Nicotinamid Adenine Dinucleotide Phosphate (NADPH) oxidase. Therefore, CGD increases the body’s susceptibility to infections caused by bacteria and fungi with granulomas formed at the sites of infection or inflammation. We report 4 cases diagnosed as suspected CGD in patients suffering from persistent pneumonia in the respiratory unit in Vietnam National Children’s Hospital to recommend colleagues not to mis-diagnose CGD in recurrent or persistent pneumonia.
Appears in CollectionsLĩnh vực Khoa học sức khỏe




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