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Authors: Trinh Le Huy, Pham Duy Manh (2021) - Gastrointestinal metastasis in lung cancer is not commonly encountered clinically, of which rectal involvement
is a sporadic event. There were few reports about rectal metastasis in lung cancer. All of them had a dismal
prognosis. We report a case of synchronous rectal metastasis in a lung cancer patient with a different clinical
scenario, treatment, and prognosis. The patient presented with infrequent hematochezia due to a rectal mass
confirmed as adenocarcinoma on core biopsy. Computer tomography showed many nodules in both lungs,
which raised the initial diagnosis of pulmonary metastasis in rectal cancer
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Authors: Phạm Văn Tú, Phạm Thu Hằng; Đỗ Thị Huyền Trang (2021) - Mục tiêu của nghiên cứu nhằm nhận xét tình trạng tăng acid uric máu không triệu chứng và một số yếu tố liên
quan ở nam giới đến khám tại Bệnh viện Đại học Y Hà Nội với 798 nam giới từ 18 tuổi trở lên từ tháng 1 năm 2020
đến tháng 5 năm 2021. Thiết kế nghiên cứu mô tả cắt ngang. Kết quả nghiên cứu cho thấy tỷ lệ tăng acid uric máu
không triệu chứng là 41,4%, nồng độ acid uric máu trung bình là 405,2 ± 81,2 µmol/l (cao nhất là 820 µmol/l ), hay
gặp nhất ở nhóm từ 40 đến 59 tuổi (chiếm 48,3%). Uống rượu bia, tăng huyết áp, thừa cân/ béo phì, rối loạn lipid
máu là yếu tố nguy cơ gây tăng acid uric máu (p < 0,05). Có mối tương quan đồng biến giữa nồng độ acid uric máu
với nồng độ Cholesterol toàn phần, Triglycerid máu (p < 0,05). Tình trạng tăng acid uric máu không triệu chứn...
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Authors: Tran Thai Ha, Pham Thi Van Anh; Dao Xuan Tinh (2021) - “Tran chau nguu hoang hoan” was prepared from 12 herbal ingredients. So far, the safety of this product,
has not been reported yet. Thus, this study aimed to evaluate the acute and subchronic toxicity of “Tran chau
nguu hoang hoan” through oral administration in experimental animals. The acute toxicity was determined
by the method of Litchfield Wilcoxon in mice at the doses of 2.42 g/kg b.w/day to 6.04 g/kg b.w/day. The
subchronic toxicity was evaluated followed the Guideline of WHO and OECD in rats with oral doses of 58.0
mg/kg b.w/day and 174.0 mg/kg b.w/day for 12 consecutive weeks. As a result, in the course of the acute
toxicity test, the mice showed no abnormal sign or death. In terms of the subchonic toxicity test, hematological
indexes, hepato-renal functions a...
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Authors: Pham Thi Van Anh, Tran Thai Ha; Ta Minh Nguyet (2021) - It has recently become obvious that the prevalence of obesity has been rapidly increasing in Vietnam,
as well as other countries, over the past two decades. There has been a current trend for researchers to
discover new natural ingredients which are safe and effective in the treatment of obesity. RABELLA powder
was a herbal-derived product which contained Amorphophalus konjac (K. Koch starch).
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Authors: Lê Hoàn, Lê Minh Hằng; Nguyễn Thị Như Quỳnh (2021) - GeneXpert là một trong những kỹ thuật sinh học phân tử hàng đầu được Tổ chức Y tế thế giới (TCYTTG)
khuyến cáo sử dụng trong chẩn đoán bệnh lao hiện nay. Nghiên cứu của chúng tôi được tiến hành nhằm
đánh giá vai trò của xét nghiệm GeneXpert đờm trong chẩn đoán lao phổi, đặc biệt ở những đối tượng xét
nghiệm AFB trong đờm âm tính. Nghiên cứu cắt ngang mô tả được thực hiện trên 1069 trường hợp có triệu
chứng hoặc hình ảnh X quang lồng ngực nghi ngờ lao phổi. Nam giới và nữ giới chiếm tỷ lệ tương đương trong
nghiên cứu. Các triệu chứng lâm sàng thường gặp bao gồm: ho (81,7%), đau ngực (21,5%), khó thở (20,5%),
mệt mỏi (11,9%), sốt (11%). Hình ảnh X-quang lồng ngực nghi ngờ nhiễm lao chiếm 88,6%. Xét nghiệm tìm
AFB trực tiếp trong đờm dương tính chiếm 3% tổng số bệnh nhân....
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Authors: Ha Thi Yen, Tran Thanh Tung (2021) - The purpose of this research was to evaluate the acute and subchronic toxicities of An Phu Khang
capsules through oral administration in experimental animals. The acute toxicity was determined by the
method of Litchfield Wilcoxon in Swiss mice. The subchronic toxicity was evaluated by the recommendation
of WHO in Wistar rats at these doses of 0.54 g/kg b.w/day (equal to recommended human dose) and 1.62
g/kg b.w/day (3 times as high as recommended human dose) in 4 consecutive weeks. As a result
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Authors: Pham Thi Van Anh, Nguyen Phuong Thanh; Dau Thuy Duong (2021) - A double-blind, randomized, phase II clinical trial was conducted within a 14-week follow-up including 2 weeks
of the non-drug run-in period, 8 weeks of medication, and 4 weeks of follow-up after discontinuation. The objective
of the study was to evaluate the efficacy and safety of Trang Phuc Linh Plus in irritable diarrhea syndrome patients.
Group I took Trang Phuc Linh Plus 3 tablets/time x 2 times/day for 8 weeks; Group II took placebo 3 tablets/
time x 2 times/day for 8 weeks. Patients will be re-examined, tested, and evaluated over the phone for symptom
recurrence and adverse events (AEs). This study showed that the Trang Phuc Linh Plus tablets tended to improve
symptoms in patients suffering from irritable bowel syndrome with diarrhea, suggesting its safety and tole...
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Authors: Trinh Le Huy, Pham Duy Manh (2021) - A 45-year-old male presented with symptoms mimicking pericarditis, including rapidly worsening dyspnea
and retrosternal chest pain. On imaging workup, an abnormal mass of 50x53 mm in size was detected at the
left atrium, which partially obstructed blood flow through the mitral valve. PET/CT was done in searching for
the probable site of origin but revealed no abnormal uptake lesions. The tumorectomy and excision of the
posterior wall of the left atrium were then performed with curative intent. The postoperative histology of the
tumor was in favor of a spindle cell sarcoma, originating from the left atrium, grade 2, which was confirmed as
epithelioid angiosarcoma by immunohistochemistry. The patient denied adjuvant radiation, thus we treated him
with six cycles of Pacli...
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Authors: Tran Thanh Tung, Trinh Vinh Quang (2021) - This study was performed to investigate the effects of An Tri Khang (ATK) hard capsule on scopolamine induced memory impairment in experimental animals. The effects on memory of oral administration ATK
were evaluated on scopolamine-induced memory impairment in experimental animals. The memory
improvement effects were conducted on 2 experimental models: the Morris water maze (MWM) and
the Multi-T maze (MTM). In the MWM model, ATK significantly reduced the time spent and pathlength
to platform, increased the percentage of time swimming in platform’s quadrant. Swiss mice performed the
MTM with shorter in both the time spent and the pathlength to the goal box (p < 0.01). Both doses of ATK
attenuated scopolamine-mediated impairment of memory. ATK has potential effects on memo...
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Authors: Nguyen Hoai Bac, Nguyen Cao Thang (2021) - Congenital penile curvature (CPC) is a rare condition in men but has considerable impact on male
sexual activity as well as their mental health. Many techniques had been proposed to manage this condition,
however the corporal rotation technique had the advantage of preserving the penile length. Therefore, we
conducted a study on 16 men with CPC who were treated with corporal rotation surgery to evaluate the
outcome of this technique. The results showed that the mean degree of curvature was 51 ± 12.2 degree.
The majority of patients had a moderate penile curvature (< 60 degree) and ventral curvature (75%). After
the surgery, the residual curvature decreased significantly (from 51 ± 12.2 degree to 16.6 ± 6.34 degree with
p < 0.001). We observed no remarkable changes in a...
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