ArticleAuthors: Nguyen Thi Quynh Nga, Nguyen Thi Van (2021)
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that is most commonly seen in premature
infants who require prolonged mechanical ventilation and oxygen therapy. 75% of intubated infants have
episodes of dysfunctional surfactants associated with lower levels of surfactant proteins. This study aims to
evaluate the effectiveness of late surfactant therapy in treating BPD in premature infants. Nineteen preterm
infants diagnosed with severe BPD requiring mechanic ventilation, according to Jobe and Bancalari, were
treated with surfactant (Poractant alpha 100mg/kg intra-tracheal). 
