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    Browsing by Subject subchronic toxicity

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    • Article

    • Subchronic oral toxicity of rabella powder in experimental rats

      • Authors: Pham Thi Van Anh, Tran Thai Ha; Ta Minh Nguyet (2021)

    • It has recently become obvious that the prevalence of obesity has been rapidly increasing in Vietnam, as well as other countries, over the past two decades. There has been a current trend for researchers to discover new natural ingredients which are safe and effective in the treatment of obesity. RABELLA powder was a herbal-derived product which contained Amorphophalus konjac (K. Koch starch).
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    • magazine

    • Subchronic toxicity evaluation of diatarin in experimental animals

      • Authors: Dinh Thi Thu Hang; Pham Thi Van Anh; Vong Binh Long (2020)

    • Diatarin was a product of the Ipharm Vietnam Pharmaceutical Joint Stock Company. So far, the safety of Diatarin has not been reported yet. Thus, this study was to investigate the subchronic oral toxicity of Diatarin at doses of 163.2 mg/kg b.w/day and 489.6 mg/kg b.w/day in rats during consecutive 12 weeks following the recommendation of WHO and OECD
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    • Article

    • The study of acute and subchronic toxicities of Da Dai Trang HVD capsules in experimental animals

      • Authors: Pham Thi Van Anh, Nguyen Van Dam (2021)

    • The purpose of this research is to evaluate the acute and subchronic toxicities of DA DAI TRANG HVD capsules through oral administration in experimental animals. The acute toxicity was determined by the method of Litchfield Wilcoxon in Swiss mice. The subchronic toxicity was evaluated by the recommendation of WHO and OECD in Wistar rats with oral doses of 1.44 g/kg/day (equal to recommended human dose) and 4.32 g/kg/ day (3 times as high as recommended human dose) in 4 consecutive weeks. As a result, DA DAI TRANG HVD capsules at the highest dose used for mice (99.9 g materials/kg) did not express acute toxicity in mice. In term of the subchonic toxicity test, DA DAI TRANG H...