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  • Article

  • St-elevation myocardial infraction complicated by cardiac arrest in a young patient with familial dyslipidemia

    • Authors: Pham Minh Tuan, Doan Tuan Vu (2021)

  • Coronary heart disease in young patients always poses great challenges for every healthcare system with differences in clinical manifestations, etiology, epidemiology, angiographic characteristics and prognosis. The objective of this study was to describe a case of ST-elevation myocardial infarction complicated by cardiac arrest in a young patient with familial dyslipidemia. A 30-year-old male visited our hospital with typical angina. During the examination, he suffered a sudden loss of consciousness, the monitor showed ventricular fibrillation. After successful resuscitation of cardiac arrest, electrocardiography showed apparent ST-elevation from V2 to V6 leads consistent with the diagnosis of anterolateral infarction
  • Article

  • Prevalence and related factors of alcohol consumption among ethnic minority boarding high schoolers in southern Vietnam

    • Authors: Nguyen Thanh Binh, Le Thi Diem Trinh; Pham Duy Quang (2021)

  • Hazardous levels of alcohol use have caused many diseases, posing a great economic and social burden to the community. Alcohol use in some provinces of Vietnam shows that alcohol consumers are getting younger and younger. This study aimed to determine the proportion of alcohol consumption among students at Binh Phuoc Ethnic Minority High School in 2020 and a number of factors leading to the alcohol consumption. The result showed that the alcohol use proportion in the past 12 months was 62% and the risky drinkers rate was 11.2%. Some factors concerning the use of alcohol among students such as gender, age, grade level, behavior, smoking, alcohol use family members, alcoholic friends, and friends influence were also revealed in the study
  • Article

  • The study of acute and subchronic toxicities of Da Dai Trang HVD capsules in experimental animals

    • Authors: Pham Thi Van Anh, Nguyen Van Dam (2021)

  • The purpose of this research is to evaluate the acute and subchronic toxicities of DA DAI TRANG HVD capsules through oral administration in experimental animals. The acute toxicity was determined by the method of Litchfield Wilcoxon in Swiss mice. The subchronic toxicity was evaluated by the recommendation of WHO and OECD in Wistar rats with oral doses of 1.44 g/kg/day (equal to recommended human dose) and 4.32 g/kg/ day (3 times as high as recommended human dose) in 4 consecutive weeks. As a result, DA DAI TRANG HVD capsules at the highest dose used for mice (99.9 g materials/kg) did not express acute toxicity in mice. In term of the subchonic toxicity test, DA DAI TRANG HVD had no deleterious effect on hematological parameters, hepato-renal functions, macroscopic and ...
  • Article

  • Sub-chronic oral toxicity study of "Kien Nao Dan" tablets in experimental animal

    • Authors: Le Thanh Xuan, Le Thi Nhat Ngoc (2021)

  • The present study aimed to investigate the sub-chronic toxicity of “Phong thap dan” (PTD) tablets through oral administration in experimental animal. The sub-chronic toxicity was evaluated by the WHO recommendation in Wistar rats at doses of 0.72 g/kg/day (equal to recommended human dose) and 2.16 g/kg/day (3 times as high as recommended human dose). In the sub-chronic experimental group, the PTD was administered orally daily for 8 consecutive weeks. In the evaluation of sub-chronic toxicity, there were no behavioral and physiological change or sign of toxicity. The result of the hematological and biological parameters after administration of PTD tablets showed no change. The histopathology analysis of livers and kidneys indicated that no significant difference was obs...
  • Article

  • Sub-chronic oral toxicity study of "Phong Thap Dan" tablets in experimental animal

    • Authors: Trinh Thi Thuy Hong, Le Thanh Xuan; Tran Quang Minh (2021)

  • “Kien nao dan” (KND) tablet is composed of 13 traditional medicines that may has preventive and effective treatment of cerebral ischemia. However, there are no scientific reports of its toxicological properties which guarantee of the safety its usage treatment. Therefore, the aim of this study was to investigate the sub-chronic toxicity of KND tablet on rats through oral administration. The sub-chronic toxicity was evaluated by the recommendation of WHO in Wistar rats at doses of 0.72 g/kg/day (equal to recommended human dose) and 2.16 g/kg/day (3 times as high as recommended human dose) for 8 consecutive weeks. In the evaluation of sub-chronic toxicity, there were no behavioral and physiological changes or signs of toxicity. The result of the hematological and biologi...
  • Article

  • Nutritional status of patients undergoing upper gastrointestinal cancer surgery: a cross-sectional study at a single centre

    • Authors: Tran Hieu Hoc, Nguyen Duy Hieu; Pham Van Phu (2021)

  • Malnutrition is closely related to the outcome of disease treatment, especially in digestive cancer surgery. The aim of this study was to assess the nutritional condition of pre-operative patients with upper digestive cancers (including stomach and oesophagus) at the Department of General Surgery, Bach Mai Hospital in 2016. We conducted a cross-sectional descriptive analysis of 76 malignancies of the upper gastrointestinal tract with surgical treatments
  • Article

  • Cerebral venous sinus thrombosis relate to vaccine-induced immune thrombotic thrombocytopenia: first reported case in Viet Nam

    • Authors: Hoang Bui Hai, Do Giang Phuc; Nguyen Thanh Chung (2021)

  • Vaccination remains one of the most important public health interventions to control and mitigate the impacts of COVID-19 worldwide. A number of post-vaccination reactions have caused concern and are the cause of vaccine hesitancy. Vaccine-induced immune thrombotic thrombopenia (VITT) has been reported in several countries such as Norway at a rate of 1 per 26000 doses of the ChAdOx1 nCoV vaccine (AstraZeneca), 15 per 8 million doses of Ad26.COV2.S (Janssen; Johnson & Johnson) vaccines in the US. In Vietnam, 11.5 million doses of AstraZeneca vaccine have been administered since the commencement of a nation wide vaccination program five months ago. We report the first case of cerebral venous thrombosis related to VITT which was promptly diagnosed and successfully treated w...
  • Article

  • A case report of refractory congenital chylous ascites in infant - surgical treatment with fibrin glue

    • Authors: Nguyen Van Tinh, Nguyen Thi Viet Ha (2021)

  • Congenital chylous ascites is a rare disease that results from abnormal development of the intra-abdominal lymphatic system. No gold standard treatment has been described so far, however, a combination of medium–chain triglyceride based diet or total parenteral nutrition along with octreotide and abdominal paracentesis is considered as a conservative management. This treatment is often a challenge to physicians since chylous ascites is often refractory and result in malnutrition and immune deficiency because of the loss of proteins and lymphocytes. We report a four-month old boy with congenital chylous ascites who was refractory to medical treatment with prolonged bowel rest, total parenteral nutrition, octreotide and repeated paracentesis. The baby well responded to sur...
  • Article

  • Analgesic activity of Phong Thap Dan tablets in animal models

    • Authors: Le Thi Nhat Ngoc, Le Thanh Xuan (2021)

  • Phong thap dan tablets are intended to treat low back pain. This study was carried out to evaluate the analgesic effects of Phong thap dan tablets in experimental animals. The analgesic effects were evaluated in three animal models: hot plate, mechanical stimulation and acetic acid-induced writhing test. Mice were divided into 4 groups given oral water, control drug (codein phosphate in hot plate and mechanical stimulation tests or aspirin in writhing test), Phong thap dan at 2.88 tablets (1.44 g) or 8.64 tablets (4.32 g)/kg b.w/day, respectively. Our results showed that Phong thap dan tablets at both doses increased the reaction time to thermal stimulation, increased the paw withdrawal latency and the force required to elicit a paw withdrawal and decreased the number ...
  • Article

  • Đặc điểm lâm sàng, cận lâm sàng và xử trí u nhầy buồng trứng tại bệnh viện phụ sản trung ương

    • Authors: Nguyễn Thị Nga, Nguyễn Quốc Tuấn; Lê Thị Hương Lan (2022)

  • U nhầy buồng trứng đại diện cho một loạt các rối loạn tân sinh. U nhầy là loại u dễ tái phát và có khả năng biến chứng nguy hiểm nếu xử trí không đúng dù là lành tính. Nghiên cứu hồi cứu 240 hồ sơ bệnh án bệnh nhân u nhầy buồng trứng đã được phẫu thuật. Kết quả: 74,6% u nhầy lành tính, giáp biên 10,4%, ác tính 15,0%, tuổi ≥ 50 có tỷ lệ ác tính cao 25,0%. Triệu chứng đau bụng hay gặp 48,5%, bụng to lên nhanh và gầy sút cân là dấu hiệu gợi ý ác tính. Nếu U nhầy có đặc điểm: ở hai bên, kích thước từ 16 - 20cm, không di động, mật độ không đều, cứng chắc có tỷ lệ ác tính cao. Trên siêu âm hình ảnh âm vang hỗn hợp có tỷ lệ ác tính cao 63,0%. U nhầy lành tính có tỷ lệ mổ nội soi thành công cao 72,2%, u ác tính thường mổ mở 61,1%. Tỷ lệ bóc u 33,3%, cắt bỏ buồng trứng chung 66...