ArticleAuthors: Le Thanh Xuan, Le Thi Nhat Ngoc (2021)
The present study aimed to investigate the sub-chronic toxicity of “Phong thap dan” (PTD) tablets
through oral administration in experimental animal. The sub-chronic toxicity was evaluated by the WHO
recommendation in Wistar rats at doses of 0.72 g/kg/day (equal to recommended human dose) and 2.16
g/kg/day (3 times as high as recommended human dose). In the sub-chronic experimental group, the PTD
was administered orally daily for 8 consecutive weeks. In the evaluation of sub-chronic toxicity, there were
no behavioral and physiological change or sign of toxicity. The result of the hematological and biological
parameters after administration of PTD tablets showed no change. ... 
